Author's response to reviews Title: Destructive arthritis in a patient with chikungunya virus infection with persistent specific IgM antibodies Authors:

Destructive arthritis in a patient with chikungunya virus infection with persistent specific IgM antibodies

BACKGROUND Chikungunya fever is an emerging arboviral disease characterized by an algo-eruptive syndrome, inflammatory polyarthralgias, or tenosynovitis that can last for months to years. Up to now, the pathophysiology of the chronic stage is poorly understood. CASE PRESENTATION We report the first case of CHIKV infection with chronic associated rheumatism in a patient who developed progressi...

Undifferentiated arthritis: predictive factors of persistent arthritis and treatment decisions

A number of patients with inflammatory arthritis due to inadequate clinical or laboratory data do not fulfill diagnostic criteria for a clinical disease categories. These patients with initial diagnosis of undifferentiated arthritis (UA) may remit or progress to a definite well- defined condition such as rheumatoid arthritis (RA) or remain as UA with persistence of inflammatory arthritis. The m...

Author's response to reviews Title: Supplemental treatment of rheumatoid arthritis with natural milk antibodies against enteromicrobes and their toxins: results of an open-labeled pilot Authors:

Congenital Chikungunya with Centro-facial Pigmentation and Persistent Thrombocytopenia: A Case Report

Hyperpigmentation over face in a neonate is rare and the differentials for the same are also rare. Congenital chickengunya, fungal and viral infections, drug rash are few differentials. Chikungunya virus (CHIKV) infection manifesting in neonates is very rare. The prevalence of the entity was described only recently. We describe a neonate with hyperpigmentation on day 3 of life with stormy cours...

Prevalence of serum antibodies to TORCH infection in the first trimester of the pregnancy in Kashan, Iran

Introduction:TORCH infections causing via Toxoplasma gondii, other microorganisms (e.g., Treponema pallidum), Rubella virus, Cytomegalovirus (CMV) and the Herpes Simplex Virus (HSV) types 1 and 2 during the first trimester of pregnancy can lead to severe fetal anomalies or even fetal loss. The current study determined the serological data of TORCH infections in women who were in their first tri...